🌸 Tranexamic Acid (TXA)

Tranexamic acid (TXA) is a synthetic derivative of the amino acid lysine. Originally used in medicine to reduce bleeding, it has since gained acclaim in dermatology for its powerful effects on melasma, dark spots, and post-inflammatory hyperpigmentation (PIH). Unlike harsh depigmenting agents, TXA is gentle yet highly effective, making it a trusted ingredient for glowing, even-toned skin—especially for women with pigmentation concerns linked to hormones, sun exposure, or acne.

💎 How Tranexamic Acid Enhances Skin Beauty
1. Targets Stubborn Pigmentation
Inhibits plasminogen activation, reducing the release of inflammatory mediators that trigger melanin overproduction.

Especially effective for melasma, PIH, and sunspots—conditions often resistant to conventional brightening agents.

2. Reduces Redness & Inflammation
Calms skin affected by rosacea, acne-induced discoloration, or inflammatory hyperpigmentation.

3. Safe for Long-Term Use
Unlike hydroquinone, TXA does not bleach skin, making it suitable for sensitive or darker skin types and long-term daily application.

4. Boosts Radiance
Regular use improves skin clarity, restores brightness, and leaves the complexion looking refined and luminous.

🧴 Usage Forms
Topical serums or creams (2–5% TXA), ideal for daily AM/PM use

Oral supplements (250–500 mg/day) prescribed by dermatologists for stubborn melasma or systemic pigmentation issues

Combined formulas with niacinamide, vitamin C, or glutathione for synergistic effects

👩 Ideal For
Women dealing with hormonal pigmentation (e.g., melasma during pregnancy)

Those with acne marks, post-laser discoloration, or sun-damaged skin

Skin brightening routines for glow enhancement without irritation

📚 Evidence-Based Results
Topical TXA (5%) showed significant reduction in melasma after 12 weeks of use, comparable to 4% hydroquinone but with fewer side effects.

Oral TXA (250 mg twice daily) improved melasma scores in 90% of participants within 8–12 weeks.

📘 Scientific References (APA Style)
Lee, H. C., Thng, T. G., Goh, C. L., & Pang, S. M. (2016). Oral Tranexamic Acid Lightens Refractory Melasma. Journal of Clinical and Aesthetic Dermatology, 9(1), 29–33.

Del Rosario, E., Florell, S., & Leachman, S. A. (2021). Tranexamic acid in dermatology: A review of its uses and efficacy. Dermatologic Surgery, 47(5), 644–650. https://doi.org/10.1097/DSS.0000000000002584

Maeda, K., & Naganuma, M. (1998). Topical trans-4-aminomethylcyclohexanecarboxylic acid prevents ultraviolet radiation-induced pigmentation. Journal of Photochemistry and Photobiology B: Biology, 47(2–3), 136–141.